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The antibiotics crisis

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As people are really busy taking about climate change, there's another real issue and that is antibiotics, namely the global overuse of them. I don't see climate changing killing much anyone in western societies but a future without antibiotics would be lethal. Here's a polemic article about them. Long story short, surgery (anyone had a surgery? I have) could become lethal, minor cuts could kill, heart transplant would be impossible and so on.

As ex-libertarian I can say that antibiotics is probably one of the best examples of tragedy of commons we know. Basically anyone who uses them does not pay the externality costs completely, and can extract huge rents. Any kind of Coasean solution has not happened and is not going to happen. There's already plenty of evidence that this can be fixed, and indeed has been fixed (here for example) with proper regulation.
3 out of 10 people who contracted pneumonia before antibiotics were used, died.
23 0000 people die each year as a direct result of antobiotic-resistant infection
80% of all antobiotics are used on farm animals

Here are some articles in scientific medial journals:
The continuing crisis in antibiotic resistance

The emergence of antibiotic resistance in bacterial pathogens is an inevitable consequence of antibiotic use. Despite repeated warnings, negligent antibiotic use and poor infection-control practice have led to the continuing development of extensive resistance problems worldwide. Multidrug-resistant pathogens are now characterized by their heterogeneity, increasing virulence, resistance even to reserve agents and spread within and between hospitals and the community. Examples are glycopeptide-resistant meticillin-resistant Staphylococcus aureus (MRSA) and enterococci, extended-spectrum β-lactamase- and carbapenemase-producing coliforms, and toxin-hyperproducing Clostridium difficile. Effective national and international programmes of control to combat these problems are urgently needed. The potential for success of such coordinated efforts has been demonstrated by the recent dramatic reductions in MRSA and C. difficile infections in England.
The Crisis in Antibiotic Resistance

The synthesis of large numbers of antibiotics over the past three decades has caused complacency about the threat of bacterial resistance. Bacteria have become resistant to antimicrobial agents as a result of chromosomal changes or the exchange of genetic material via plasmids and transposons. Streptococcus pneumoniae, Streptococcus pyogenes, and staphylococci, organisms that cause respiratory and cutaneous infections, and members of the Enterobacteriaceae and Pseudomonas families, organisms that cause diarrhea, urinary infection, and sepsis, are now resistant to virtually all of the older antibiotics. The extensive use of antibiotics in the community and hospitals has fueled this crisis. Mechanisms such as antibiotic control programs, better hygiene, and synthesis of agents with improved antimicrobial activity need to be adopted in order to limit bacterial resistance.

A Call to Arms: The Imperative for Antimicrobial Stewardship

Antimicrobial resistance is a major public health crisis. The prevalence of drug-resistant organisms, such as the emerging NAP1 strain of Clostridium difficile, now highly resistant to fluoroquinolones, Acinetobacter species, Klebsiella pneumoniae carbapenemase-producing organisms, and methicillin-resistant Staphylococcus aureus, is increasing nationwide. The sources of antimicrobial resistance are manifold, but there is a well-documented causal relationship between antimicrobial use and misuse and the emergence of antimicrobial-resistant pathogens. As the development of new antimicrobial agents is on the decline, the medical community, across all specialties and in conjunction with public health services, must develop and implement programs and strategies designed to preserve the integrity and effectiveness of the existing antimicrobial armamentarium. Such strategies are collectively known as antimicrobial stewardship programs and have the potential to minimize the emergence of resistant pathogens.

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